Mayo Clinic Minute: Treating Dupuytren contracture without surgery

Dupuytren contracture is a disorder that can cause the fingers to curl in, primarily the ring and small fingers.

It’s a genetic condition mostly affecting men over 60 of Northern European descent. Others at risk include people with diabetes and those with a family history of the condition.

“What happens in Dupuytren’s disease is the layer of fascia that is underneath the skin in the palm gets thickened and contracted,” says Dr. Shelley Noland, a Mayo Clinic hand and peripheral nerve surgeon.

That can make your fingers curl in. It’s not painful, but Dr. Noland says, “It can cause significant functional limitations because the patients are unable to fully straighten out their fingers.”

Dupuytren contracture is a condition that causes one or more fingers to bend toward the palm of the hand. The affected fingers can’t straighten completely. It most often affects the two fingers farthest from the thumb.

Patients with advanced disease will need an intervention to relieve the contracture. There are several treatment options. An enzyme injection is a newer, less invasive treatment.