MINNEAPOLIS (AP) — Josh Allen played with the poise of a well-seasoned quarterback for the Buffalo Bills by accounting for three touchdowns in his first road start in the NFL. Allen made Minnesota’s Kirk Cousins look like the raw rookie in a stunning 27-6 upset of the Vikings on Sunday.
The Vikings (1-1-1) were 16½-point favorites when the game began, allowing the Bills (1-2) to become only the sixth such underdog in the NFL’s last 81 point spreads that big. After being outscored 75-9 over their first six quarters of the season, the Bills have enjoyed a 41-9 advantage over the last six periods.
SAINTS 43, FALCONS 37, OT
ATLANTA (AP) — Drew Brees’ 1-yard run capped an 80-yard touchdown drive to open overtime. Brees’ score came after his apparent 3-yard TD pass to Alvin Kamara was overturned on video review that determined Kamara’s knee was down before the goal line. Brees scored on a keeper on the following play, giving the Saints (2-1) the win on the day the 39-year-old quarterback set the NFL record for career completions.
Brees passed for 396 yards and three touchdowns and ran for two scores. Kamara had 15 catches for 124 yards and ran for 66 yards. Atlanta’s Matt Ryan had his first career game with five scoring passes, including three to rookie Calvin Ridley. That wasn’t enough for the Falcons (1-2) against the high-scoring Saints, who gained 534 yards.
EAGLES 20, COLTS 16
PHILADELPHIA (AP) — Carson Wentz threw a touchdown pass on his first drive in nine months, then Wendell Smallwood ran in from the 4 for the go-ahead score.
The defending Super Bowl champion Eagles (2-1) needed two defensive stops against Andrew Luck in the final 90 seconds. Indy had a first down at the Eagles 11 and two cracks from the 4, but Luck’s pass to T.Y. Hilton sailed over his shoulder in the left corner of the end zone on third down and Derek Barnett sacked Luck on fourth down.
RAMS 35, CHARGERS 23
LOS ANGELES (AP) — Jared Goff passed for 354 yards and three touchdowns, and Todd Gurley rushed for 105 yards and another score, leading the Rams over the Chargers in the franchises’ first meeting since their relocations to Los Angeles.
Cory Littleton blocked a punt in the end zone and Blake Countess recovered for an early touchdown for the Rams (3-0), who racked up 521 yards and remained one of the NFL’s four unbeaten teams. Philip Rivers passed for 226 yards and hit Mike Williams with two touchdown passes for the Chargers (1-2), whose two losses have come against the powerhouse Chiefs and Rams without injured pass rusher Joey Bosa. Melvin Gordon rushed for 80 yards and a score.
SEAHAWKS 24, COWBOYS 13
SEATTLE (AP) — Russell Wilson threw for two touchdowns in the first half, Chris Carson added a 5-yard TD run in early in the fourth quarter, and the Seahawks avoided an 0-3 start.
Wilson hit Jaron Brown on an 18-yard touchdown early in the second quarter, and later found Tyler Lockett streaking up the sideline on a 52-yard scoring pass as Seattle (1-2) built a 17-3 halftime lead and cruised past the Cowboys.
The duo of Dak Prescott and Ezekiel Elliott didn’t have the answers against a Seattle defense that had safety Earl Thomas on the field and welcomed back Bobby Wagner after the Seahawks’ defensive leader missed Week 2 with a groin injury. Prescott was sacked five times and Dallas (1-2) had just 58 net yards passing entering the fourth quarter. Elliott had momentary flashes, busting off a few long runs, but they were too infrequent for Dallas’ stagnant offense.
CHIEFS 38, 49ERS 27
KANSAS CITY, Mo. (AP) — After winning his first three starts, all away from Arrowhead Stadium, second-year pro Patrick Mahomes finally made his regular-season home debut and torched San Francisco’s banged-up pass defense for 314 yards and three touchdowns. Mahomes now has 13 touchdown passes without an interception, breaking the NFL record for TD passes in the first three weeks of a season. Peyton Manning threw 12 to start the 2013 campaign.
Mahomes’ touchdown passes to Chris Conley, Demetrius Harris and Sammy Watkins , along with a pair of TD runs by Kareem Hunt, helped Kansas City (3-0) race to a 35-7 lead late in the first half. The 49ers (1-2) rallied behind running backs Matt Breida and Alfred Morris, who kept gouging the Chiefs’ defensive front, and Jimmy Garoppolo, who threw for 251 yards and two scores . It was Garoppolo’s 11-yard pass to Marquis Goodwin early in the third quarter that started the comeback, and Morris scored on a short touchdown run later in the quarter to make it 35-24. But Garoppolo was injured on a late run and was feared to have his left ACL.
DOLPHINS 28, RAIDERS 20
MIAMI GARDENS, Fla. (AP) — Receiver Albert Wilson threw a 52-yard touchdown pass to put the Dolphins ahead midway through the fourth quarter, and then turned a short reception into a 74-yard score that sealed it.
Thanks to all the flashy plays, the Dolphins are 3-0 for only the third time since 1998. The Raiders, led by first-year coach Jon Gruden, are 0-3 for the first time since 2014, when they started 0-10.
RAVENS 27, BRONCOS 14
BALTIMORE (AP) — Joe Flacco picked apart Denver’s depleted defense for 277 yards and a touchdown. Connecting with eight receivers, Flacco went 25 for 40 without an interception on a rainy afternoon. He threw 28 passes in the first half, when Baltimore (2-1) took control.
The Ravens turned to their defense in the fourth quarter, twice stopping drives inside their 15.
TITANS 9, JAGUARS 6
JACKSONVILLE, Fla. (AP) — Marcus Mariota came off the bench and directed three scoring drives, including one in the fourth quarter. Mariota replaced Blaine Gabbert in the first quarter after Gabbert was knocked out of the game with a concussion.
Mariota wore a glove on his injured right hand and was able to do just enough to beat the Jaguars (2-1) for the third straight time and fifth time in the past six meetings.
The Titans (2-1) milked the clock from there and ended up celebrating an early lead in the AFC South.
REDSKINS 31, PACKERS 17
LANDOVER, Md. (AP) — Adrian Peterson ran for 120 yards and a pair of 2-yard scores, Alex Smith threw two touchdown passes — all in the first half — and the Redskins held on over a gimpy Aaron Rodgers and the Packers, who again had complaints about a roughing-the-passer penalty on Clay Matthews.
On a rainy afternoon, the Redskins (2-1) moved out to leads of 14-0 and, at halftime, 28-10, by putting together TD drives of 74, 75, 79 and 98 yards. Smith connected for TDs of 46 yards to Paul Richardson on the game’s fourth play and of 9 to Jamison Crowder in the second quarter. Playing with a bulky brace on his left knee, which he hurt in Week 1, Rodgers hobbled and limped around, and couldn’t do enough to get the Packers (1-1-1) back into the game. He finished 27 for 44 for 265 yards with two TDs — of 64 yards to Geronimo Allison and 2 yards to Davante Adams — and was sacked four times.
GIANTS 27, TEXANS 22
HOUSTON (AP) — Eli Manning threw for 297 yards and two touchdowns and rookie Saquon Barkley added a score.
The Giants (1-2) were up by 14 at halftime but had trouble moving the ball in the second half and the Texans (0-3) had cut the lead to five before Manning threw a 7-yard touchdown pass to Sterling Shepard with about two minutes left.
Deshaun Watson threw a 4-yard touchdown pass to Lamar Miller with 1 second left to cut the lead to 27-22, but New York recovered the onside kick. Watson threw for 385 yards and two scores, but his interception was one of two second-half turnovers by the Texans, off to their worst start since dropping their first four games of 2008.
BEARS 16, CARDINALS 14
GLENDALE, Ariz. (AP) — Cody Parkey kicked his third field goal of the game, a 43-yarder with 4:31 to remaining, to rally the Bears.
Sam Bradford threw two first-quarter touchdown passes to put the Cardinals up 14-0, but was replaced by rookie Josh Rosen after fumbling the ball deep in Chicago territory late in the game.
The Bears (2-1) intercepted three passes and recovered one fumble. Arizona is 0-3 for the first time since 2004.